Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Anxiety
ADR ID BADD_A00273
ADR Hierarchy
19      Psychiatric disorders
19.06      Anxiety disorders and symptoms
19.06.02      Anxiety symptoms
19.06.02.002      Anxiety
Description A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. [CTCAE] Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. | Condition of elevated sensory sensitivity, perception of risk of threats, and low threshhold for stimuli. | Emotion characterized by feelings of tension, worried thoughts, and inadequacy in a social setting. [MeSH]
MedDRA Code 10002855
MeSH ID D001007; D001007; D013315
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Alarm (not alarm reaction) | Angor animi | Anguish | Anxiety | Anxiety attack | Anxiety complex | Anxiety NEC | Anxiety reaction | Anxiety state | Anxiety state, unspecified | Anxiety states | Anxiety symptoms NOS | Anxiety-ridden | Anxious mood | Apprehension | Exacerbation of anxiety | Face anguish | Feeling anxious | Feeling of intense apprehension | Impending doom | Made anxiety worse | Other anxiety states | Phobic anxiety | Reaction alarm | Reaction anxiety | Situational anxiety | Worry | Anxiety aggravated | Chronic anxiety | Hypervigilance | Nervousness | Social Anxiety | Anxieties, Social | Anxiety, Social | Social Anxieties
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
5-hydroxytryptamine receptor 2AP28223T32060
5-hydroxytryptamine receptor 2BP41595T31204
5-hydroxytryptamine receptor 3AP46098T64591
Alpha-1A adrenergic receptorP35348T92609
Alpha-2A adrenergic receptorP08913T11448
Histamine H1 receptorP35367T77913
Muscarinic acetylcholine receptor M1P11229T28893
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00320Butabarbital sodium--
BADD_D00324Butorphanol--
BADD_D00325Butorphanol tartrate--
BADD_D00328Cabazitaxel--
BADD_D00329Cabergoline0.088081%
BADD_D00330Cabozantinib--
BADD_D00331Cabozantinib s-malate--
BADD_D00335Calcitonin--
BADD_D00336Calcitonin (salmon)--
BADD_D00337Calcitriol--
BADD_D00343Californium-249 oxide--
BADD_D00344Canagliflozin--
BADD_D00346Candesartan--
BADD_D00347Candesartan cilexetil--
BADD_D00349Capecitabine--
BADD_D00356Carbamazepine--
BADD_D00359Carbidopa--
BADD_D00363Carbonic acid--
BADD_D00364Carboplatin--
BADD_D00365Carboprost--
BADD_D00366Carboprost tromethamine--
BADD_D00367Carfilzomib--
BADD_D00369Cariprazine0.001806%
BADD_D00371Carmustine--
BADD_D00374Carvedilol--
BADD_D00376Caspofungin--
BADD_D00377Caspofungin acetate--
BADD_D00378Cefaclor--
BADD_D00379Cefadroxil0.002555%
BADD_D00395Cefpodoxime--
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